Superior Vena Cava Thrombosis in a Case of Lung Adenocarcinoma
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چکیده
♦Corresponding Author: Kaushik Saha, MD Rabindra Pally, 1st Lane, P.O. Nimta, Kolkata – 700049, West Bengal, India Tel: +919433383080, +91033-25396689 Email: [email protected] Introduction Superior vena cava (SVC) thrombosis is a common phenomenon secondary to subclavian catheterization, however in malignancy it is quite uncommon. Pure intravascular thrombosis is extremely rare and only 0.04% of hospitalized adults have been diagnosed with cancer-related SVC thrombosis.1,2 Patients that have SVC thrombosis usually present with clinical features of SVC syndrome. We report a rare case of SVC syndrome caused by cancer-related thrombosis. Case Report A 65-year-old male presented with progressive swelling of his face and right upper limb for one month. He was a chronic smoker for the past 30 years with a smoking index of 750. He also had dry cough since two months and a dull ache, poorly localized right-sided chest pain since the previous one month. On general survey, there was presence of mild pallor with absence of clubbing. His physical examination revealed facial puffiness, conjunctival redness, nonpulsatile engorged neck veins, and tortuous dilated superficial veins over his chest with venous flow directing above downwards towards the Abstract Superior vena cava syndrome is a common presentation of bronchogenic carcinoma. The mechanism of obstruction is by compression of superior vena cava by the bronchogenic tumor itself or enlarged mediastinal lymph nodes. However obstruction due to intravascular thrombosis is extremely uncommon. Here, we report a rare case of a 65-year-old male smoker who presented with superior vena cava syndrome and bilateral pleural and pericardial effusion with thrombotic occlusion of the superior vena cava in adenocarcinoma of the lung. He was given chemotherapy with carboplatin and gemcitabine with anticoagulant therapy.
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Superior Vena Cava Syndrome due to Thrombosis: A Rare Paraneoplastic Presentation of Bronchogenic Carcinoma
Superior vena cava (SVC) syndrome is not an uncommon occurrence in patients with malignancy and it is often described as a medical emergency. In majority of the cases, SVC syndrome occurs due to mechanical obstruction of the SVC by extraluminal compression with primary intrathoracic malignancies. However, intraluminal obstruction due to thrombosis can also produce symptoms and signs of SVC synd...
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